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21c Museum Hotel Louisville

700 W Main Street, Louisville, KY 40202 US near Exit 4 on I-64 (~0.2mi)
View Map Reservations: +1-800-219-2797
4.5 Star Property Near Louisville Slugger Museum
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Select Your Room:
03/04/2026 - 03/05/2026
Searching all hotel inventory networks
9 bookings in the last 48 hours

Standard prices by room type for the next 60 days

Rates shown are nightly rates before taxes and do not necessarily reflect all discounts available. The chart provides the cheapest public rates available by room type.

Verified Reviews of 21c Museum Hotel Louisville

Below are the verified reviews from guests that we have booked recently:
"Lovely hotel"
Overall Score4.0/ 5
We enjoyed our stay at 21c Museum Hotel. Only wish we would have had a better view. But, that is just a minor note. Everything else was perfect!
(Individual traveler, booked 1 room), from US flag
02-Jan-2026 Verified Review, stayed from Thu Jan 01 to Fri Jan 02 2026 at a $139.00 average nightly rate.
"Staff was great especially at check-in."
Overall Score5.0/ 5
Staff was great especially at check-in.
(Individual traveler, booked 1 room), from US flag
18-Sep-2025 Verified Review, stayed from Sun Sep 14 to Mon Sep 15 2025 at a $243.67 average nightly rate.
"Great Staff"
Overall Score5.0/ 5
Everyone was very helpful and we required a lot!
(Individual traveler, booked 1 room), from US flag
07-Sep-2025 Verified Review, stayed from Sat Sep 06 to Sun Sep 07 2025 at a $288.15 average nightly rate.
"Clean, great location to walk plus great bar and restaurant."
Overall Score5.0/ 5
So much to do and right in center of downtown loved it!
(Individual traveler, booked 1 room), from US flag
13-Aug-2025 Verified Review, stayed from Mon Aug 11 to Wed Aug 13 2025 at a $111.99 average nightly rate.
"Excellent Stay!"
Overall Score5.0/ 5
Hotels is right in the middle of downtown, walking distance to where you want to go. Staff and rooms were incredible. I’ll definitely be back.
(Group coordinator, booked 2 rooms), from US flag
21-Jun-2025 Verified Review, stayed from Tue Jun 17 to Thu Jun 19 2025 at a $207.20 average nightly rate.

Summary of Verified Reviews

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Review Semantics by TrustYou

Property Description

Nestled in historic downtown Louisville, 21c Museum Hotel is a 91-room boutique hotel, contemporary art museum, award-winning restaurant, and cultural civic center. Stay with us and the iconic Red Penguins, an iconic exhibition by the Cracking Art Group. As one of the most unique hotels in Louisville, KY, we pride ourselves on offering one-of-a-kind experiences for our guests who are visiting the area for business and leisure alike. Discover the plush amenities featured in our chic boutique hotel and enjoy a stay in one of our 91 luxurious guest rooms.21c is home to one of the hottest restaurants in Louisville, Proof on Main. Lauded as one of Esquire magazine’s “Best New Restaurants,” Proof is a favorite for locals and visitors alike. With a commitment to local farming, we deliver plates infused with local flavor.Whatever the occasion, if you have the people, 21c and Proof on Main have the space that will ensure your gathering is the talk of the town. With over 9,000 square feet of art-filled event space, 21c is the ideal setting for board retreats, executive meetings, cocktail gatherings, reception dinners, charitable events, weddings, or any other special occasion.

Amenities / Features


  • Check In: 4:00 pm - 12:00 am
  • Check Out: 11:00 am
  • Air conditioning
  • Alarm clock
  • ATM
  • Baby facilities in room
  • Baggage storage facilities
  • Breakfast in room
  • Central location
  • Charge for early check out
  • Concierge service
  • Conference facilities
  • Credit card accepted: Mastercard/Visa
  • Credit card accepted: American Express
  • Credit card accepted: Discover
  • Credit card accepted: Diners Club
  • Dinner available
  • Electric Car Charging Station
  • Electronic key card
  • Elevator
  • Facilities for the disabled
  • Fax available
  • Fitness and health center
  • Free local calls
  • Garage
  • Hairdryer available
  • Handicap accessible
  • Central heating
  • Ice Maker
  • Internet - wireless
  • Internet - ethernet
  • Free WiFi Internet
  • Ironing facilities
  • Laundry valet service
  • Licensed bar
  • Mini bar
  • Movies in room
  • Non-smoking rooms
  • 24 hours opened
  • Office or business center
  • Office in room available
  • Pets allowed
  • Private bathroom in room
  • Private car parking
  • Radio in room
  • Restaurant
  • Safe in rooms
  • Sauna
  • Self controlled heating/cooling system
  • Shop
  • Shower
  • Spa
  • Tea and coffee making facilities
  • Telephone in all rooms
  • Telephone - Free local calls
  • Television
  • TV - Free Cable
  • Terrace
  • Travellers cheques accepted
  • TV room
  • Valet Parking
  • Voicemail

Airport & Shuttle Information

8 miles from Louisville International Airport, $20 cab fare, one way

Airport Shuttle? Sorry, no airport shuttle available.

Pet Friendly?

Service animals complying with ADA Title lll regulations are allowed.

Yes! Pets are allowed.
$100 one-time non-refundable pet fee

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